Drug absorption
Drug absorption is a pharmacokinetic parameter that refers to the way a drug is absorbed from a pharmaceutical formulation into the bloodstream. Drugs may be either weak acids or bases that exist in both ionized and non-ionized forms in the body. Drug in the non-ionized form is adequately soluble in membrane lipids and can cross cell membranes. The rate of absorption depends upon the ratio of the 2 forms at a particular site and is also a factor in circulation and elimination.
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- Pseudo-equilibrium
- Mass Balance Approaches
- Dynamic Models
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